Glioblastoma (GBM), also mentioned as a grade IV astrocytoma, could be a fast-growing and aggressive brain tumor. This may be a form of brain cancer that’s named because the foremost common malignant tumor in adults. It invades nearby brain tissue, but generally doesn’t spread to distant organs. Although there isn’t any cure for it, some treatments can relieve its symptoms. Glioblastomas invade the brain tissue irregularly and extensively, that makes the surgical resection very difficult.
According to the young and talented Iranian neurosurgeon, Soheila Sami Aldoboni(M.D.), this tumor mostly develops within entire cerebrum but mostly in the frontal lobe of the brain in adults.
A glioblastoma neoplasm grows rapidly by creating blood vessels around it and easily destroys other healthy brain tissue. Brain tumors aren’t quite common, but if they’re doing occur, in but 20% of cases, the tumor is additionally a glioblastoma. Men are more likely than women to develop glioblastoma brain tumors, and it increases with age.
Glioblastoma belongs to the group of astrocytomas. Astrocytoma is also a mode of cancer that grows within the star-shaped cells of the brain called astrocytes. In adults, cancer usually forms within the brain. Glioblastoma tumors create blood vessels that help them grow. It is simple for these tumors to destroy the standard brain tissue. Multiple glioblastoma is also a rapidly growing brain or spinal tumor. Glioblastomas rarely spread outside the brain, spine, or central system. These tumors are very difficult to treat due to their inherent complexity.
The goal of glioblastoma treatment is to curtail and control the expansion of the tumor so that the person can live as comfortably as possible. There are four treatments for this cancer that just about all people undergo, quite one form of them :
Surgery is the primary treatment and through this process the surgeon tries to induce eliminate the most amount of the tumor as possible. In high-risk areas of the brain, it’s not possible to urge people to obviate the entire tumor.
After surgery, when the wound is healed, Radiation therapy can begin. The goal of irradiation is to selectively kill the remaining tumor cells that have infiltrated the encircling normal brain tissue.
Chemotherapy can even be helpful. Temozolomide is the most typical chemotherapy drug that doctors prescribe to treat glioblastoma. Carmustine and lomustine are other chemotherapeutic drugs accustomed to treating this kind of cancer.
Electric field therapy maintains healthy brain cells and kills cancer cells. To achieve this, doctors place electrodes directly on the scalp. This device is termed op tune. This method is utilized simultaneously with chemotherapy and after surgery and irradiation.
In the treatment of wafer (gliadel), a biodegradable implantable disc is utilized. The disc releases chemotherapy drugs into cancerous tissue left over from surgery.
Finally, in nanoparticle therapy, chemotherapy drugs are sent into the tumor using small particles. Additionally, patients can try experimental treatments or chemotherapy drugs at large cancer centers. These can help relieve symptoms and will cause cancer to withdraw from some people. Withdrawal means the disappearance of symptoms for a period of time.
This experienced neurosurgeon eventually adds even when the foremost invasive treatment is utilized, which includes radiotherapy, chemotherapy, surgery, and others. Again, the probability of the tumor returning is very high. But in cases where the goal is to increase the patient’s life longer, multiple surgeries can keep the patient alive for about one to two years, otherwise he or she sadly goes to die immediately within some months.